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Aminoacyl-tRNA synthetases - NCBI。

The discovery of the aaRSs and their role in protein synthesis began in the 50s and 60s when it was reported that amino acids were required to undergo an ...: tw | tw。

Progress and challenges in aminoacyl-tRNA synthetase-based ...。

By specifically matching amino acids to defined anticodon sequences in tRNAs, ARSs are essential to the physical interpretation of the genetic code. In addition ...: tw | tw。

New functions of aminoacyl-tRNA synthetases beyond translation。

2016年3月1日 · PDF | Over the course of evolution, eukaryotic aminoacyl-tRNA synthetases (aaRSs) progressively incorporated domains and motifs that have no ...。

Full article: Human aminoacyl-tRNA synthetases in diseases of the ...。

Aminoacyl-tRNA synthetases (AaRSs) are ubiquitously expressed enzymes that ensure accurate translation of the genetic information into functional proteins.。

Regulation of ex-translational activities is the primary function of the ...。

2020年12月21日 · Abstract. During mRNA translation, tRNAs are charged by aminoacyl-tRNA synthetases and subsequently used by ribosomes.。

Molecular basis of the multifaceted functions of human leucyl-tRNA ...。

2020年3月30日 · Leucyl-tRNA synthetase (LRS), a class I AaRS, is particularly large and complex. Structurally, LRS contains an aminoacylation domain, a tRNA ...。

Homologs of aminoacyl-tRNA synthetases acylate carrier proteins ...。

2010年8月17日 · Charged tRNAs then act as substrates for the ribosome during protein biosynthesis (1). In addition to canonical aminoacylation activity, there ...。

Aminoacyl tRNA Synthetases as Malarial Drug Targets - bioRxiv。

2018年10月11日 · Although the canonical function of these enzymes is to add amino acids to tRNA for translation and they are highly conserved in their catalytic ...。

Aminoacyl tRNA synthetases as malarial drug targets - Malaria Journal。

2019年2月6日 · Plasmodium falciparum lysyl-tRNA synthetase (PfLysRS) synthesizes diadenosine polyphosphate, a signaling molecule that plays a role in gene ...。

Virus-Encoded Aminoacyl-tRNA Synthetases - ASM Journals。

Virus-Encoded Aminoacyl-tRNA Synthetases: Structural and Functional ... M. Nilges, N. S. Pannu, R. J. Read, L. M. Rice, T. Simonson, and G. L. Warren.1998.


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